MMP16 anticorps (AA 120-296)

N° du produit ABIN5519039

Détail du produit anti-MMP16 anticorps

Antigène: MMP16 (Matrix Metallopeptidase 16 (Membrane-inserted) (MMP16))

Épitope: AA 120-296

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MMP16 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit IgG polyclonal antibody for MMP16 detection. Tested with WB, IHC-P, Direct ELISA in Human,Mouse,Rat.

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for MMP16 detection. Tested with WB, IHC-P, Direct ELISA in Human,Mouse,Rat.
Gene Name: matrix metallopeptidase 16
Protein Name: Matrix metalloproteinase-16

Purification: Immunogen affinity purified.

Immunogène: E. coli-derived huamn MMP16 recombinant protein (Position: Y120-I296).

Isotype: IgG

Information d'application

Indications d'application: Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Références pour anticorps anti-MMP16 (ABIN5519039)

Xue, Wu, Chen, Luo: "MT3-MMP down-regulation promotes tumorigenesis and correlates to poor prognosis in esophageal squamous cell carcinoma." dans: Cancer medicine, Vol. 5, Issue 9, pp. 2459-68, (2017) (PubMed).

Wang, Li, Wu, Wu, Li, Yang, Chen, Xie, Huang, Du, Zhou: "miR-132 can inhibit glioma cells invasion and migration by target MMP16 in vitro." dans: OncoTargets and therapy, Vol. 8, pp. 3211-8, (2015) (PubMed).

Détails sur MMP16

Antigène: MMP16 (Matrix Metallopeptidase 16 (Membrane-inserted) (MMP16))

Autre désignation: MMP16 (MMP16 Produits)

Synonymes: anticorps MT3-MMP, anticorps Mt3mmp, anticorps Mt3-mmp, anticorps C8orf57, anticorps MMP-X2, anticorps MT-MMP2, anticorps MT-MMP3, anticorps matrix metallopeptidase 16, anticorps Mmp16, anticorps MMP16

Sujet: The matrix metalloproteinase 16(MMP16) protein consists of 604 amino acids and has a characteristic MMP domain structure, which gene is mapped on human chromosome 8q21. Additionally, MMP16 has a C-terminal extension containing a potential transmembrane domain, similar to MMP14, MMP15, and MMP17. Furthermore, it is membrane-bound and is a member of the membrane-type MMPs that are a subclass in the MMP family since the other members lack a C-terminal transmembrane domain and are secreted as soluble forms. MMP16 is expressed as a 12-kb transcript in brain, placenta, heart, and some carcinoma cell lines, but is not detectably expressed in lung, kidney, liver, spleen, and muscle.

Synonyms: Matrix metalloproteinase-16, MMP-16, MMP-X2, Membrane-type matrix metalloproteinase 3, MT-MMP 3, MTMMP3, Membrane-type-3 matrix metalloproteinase, MT3-MMP, MT3MMP, MMP16, MMPX2

ID gène: 4325

UniProt: P51512