MMP16 anticorps (C-Term)

N° du produit ABIN657636

Cité dans 2 publications. Cet anticorps anti-MMP16 Polyclonal Lapin (Clone RB33657) (ABIN657636) détecte spécifiquement MMP16 dans WB et IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour MMP16 anticorps (C-Term) (ABIN657636)

Antigène: MMP16 (Matrix Metallopeptidase 16 (Membrane-inserted) (MMP16))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MMP16 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB33657

Détail du produit anti-MMP16 anticorps

Épitope: AA 519-548, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This MMP16 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 519-548 amino acids from the C-terminal region of human MMP16.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: MMP16 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Date de péremption: 6 months

Références pour anticorps anti-MMP16 (ABIN657636)

Wu, Ma, Shan, Zhou, Li: "High expression of matrix metalloproteinases 16 is associated with the aggressive malignant behavior and poor survival outcome in colorectal carcinoma." dans: Scientific reports, Vol. 7, pp. 46531, (2017) (PubMed).

Shen, Wang, Yu, Zhang, Qin: "MMP16 promotes tumor metastasis and indicates poor prognosis in hepatocellular carcinoma." dans: Oncotarget, Vol. 8, Issue 42, pp. 72197-72204, (2017) (PubMed).

Détails sur MMP16

Antigène: MMP16 (Matrix Metallopeptidase 16 (Membrane-inserted) (MMP16))

Autre désignation: MMP16

Sujet: Endopeptidase that degrades various components of the extracellular matrix, such as collagen type III and fibronectin. Activates progelatinase A. Involved in the matrix remodeling of blood vessels. Isoform short cleaves fibronectin and also collagen type III, but at lower rate. It has no effect on type I, II, IV and V collagen. However, upon interaction with CSPG4, it may be involved in degradation and invasion of type I collagen by melanoma cells.

Poids moléculaire: 69521

ID gène: 4325

NCBI Accession: NP_005932

UniProt: P51512