PCGF2 anticorps (AA 121-150)
Aperçu rapide pour PCGF2 anticorps (AA 121-150) (ABIN5531018)
Antigène
Voir toutes PCGF2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 121-150
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Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogène
- This PCGF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 121-150 amino acids from the Central region of human PCGF2.
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Isotype
- Ig Fraction
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Indications d'application
- For WB starting dilution is: 1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.49 mg/mL
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Buffer
- Supplied in PBS with 0.09 % (W/V) sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- PCGF2 (Polycomb Group Ring Finger 2 (PCGF2))
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Autre désignation
- PCGF2
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Sujet
- The protein encoded by this gene contains a RING finger motif and is similar to the polycomb group (PcG) gene products. PcG gene products form complexes via protein-protein interaction and maintain the transcription repression of genes involved in embryogenesis, cell cycles, and tumorigenesis. This protein was shown to act as a negative regulator of transcription and has tumor suppressor activity. The expression of this gene was detected in various tumor cells, but is limited in neural organs in normal tissues. Knockout studies in mice suggested that this protein may negatively regulate the expression of different cytokines, chemokines, and chemokine receptors, and thus plays an important role in lymphocyte differentiation and migration, as well as in immune responses.
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Poids moléculaire
- 38 kDa
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ID gène
- 7703
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UniProt
- P35227
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Pathways
- Chromatin Binding
Antigène
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