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MXI1 anticorps (AA 53-82)

Cet anticorps Lapin Polyclonal détecte spécifiquement MXI1 dans WB. Il présente une réactivité envers Humain et Souris.
N° du produit ABIN5531570

Aperçu rapide pour MXI1 anticorps (AA 53-82) (ABIN5531570)

Antigène

Voir toutes MXI1 Anticorps
MXI1 (MAX Interactor 1 (MXI1))

Reactivité

  • 33
  • 25
  • 15
  • 6
  • 5
  • 5
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
Humain, Souris

Hôte

  • 33
  • 5
  • 2
Lapin

Clonalité

  • 35
  • 5
Polyclonal

Conjugué

  • 24
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp MXI1 est non-conjugé

Application

  • 25
  • 18
  • 5
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)
  • Épitope

    • 7
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 53-82

    Purification

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    Immunogène

    This MXI1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 53-82 amino acids from the Central region of human MXI1.

    Isotype

    Ig Fraction
  • Indications d'application

    For WB starting dilution is: 1:1000

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    Supplied in PBS with 0.09 % (W/V) sodium azide.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Antigène

    MXI1 (MAX Interactor 1 (MXI1))

    Autre désignation

    MXI1

    Sujet

    Expression of the c-myc gene, which produces an oncogenic transcription factor, is tightly regulated in normal cells but is frequently deregulated in human cancers. The protein encoded by this gene is a transcriptional repressor thought to negatively regulate MYC function, and is therefore a potential tumor suppressor. This protein inhibits the transcriptional activity of MYC by competing for MAX, another basic helix-loop-helix protein that binds to MYC and is required for its function. Defects in this gene are frequently found in patients with prostate tumors. Three alternatively spliced transcripts encoding different isoforms have been described. Additional alternatively spliced transcripts may exist but the products of these transcripts have not been verified experimentally.

    Poids moléculaire

    26 kDa

    ID gène

    4601

    UniProt

    P50539

    Pathways

    Maintenance of Protein Location
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