MXI1 anticorps (AA 53-82)
Aperçu rapide pour MXI1 anticorps (AA 53-82) (ABIN5531570)
Antigène
Voir toutes MXI1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 53-82
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Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogène
- This MXI1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 53-82 amino acids from the Central region of human MXI1.
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Isotype
- Ig Fraction
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Indications d'application
- For WB starting dilution is: 1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Supplied in PBS with 0.09 % (W/V) sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- MXI1 (MAX Interactor 1 (MXI1))
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Autre désignation
- MXI1
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Sujet
- Expression of the c-myc gene, which produces an oncogenic transcription factor, is tightly regulated in normal cells but is frequently deregulated in human cancers. The protein encoded by this gene is a transcriptional repressor thought to negatively regulate MYC function, and is therefore a potential tumor suppressor. This protein inhibits the transcriptional activity of MYC by competing for MAX, another basic helix-loop-helix protein that binds to MYC and is required for its function. Defects in this gene are frequently found in patients with prostate tumors. Three alternatively spliced transcripts encoding different isoforms have been described. Additional alternatively spliced transcripts may exist but the products of these transcripts have not been verified experimentally.
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Poids moléculaire
- 26 kDa
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ID gène
- 4601
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UniProt
- P50539
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Pathways
- Maintenance of Protein Location
Antigène
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