MCM4 anticorps (C-Term)
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- Antigène Voir toutes MCM4 Anticorps
- MCM4 (Minichromosome Maintenance Deficient 4 (MCM4))
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Épitope
- AA 637-665, C-Term
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp MCM4 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogène
- This MCM4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 637-665 amino acids from the C-terminal region of human MCM4.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product MCM4 Anticorps primaire
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- Indications d'application
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For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Supplied in PBS with 0.09 % (W/V) sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- Antigène
- MCM4 (Minichromosome Maintenance Deficient 4 (MCM4))
- Autre désignation
- MCM4 (MCM4 Produits)
- Synonymes
- anticorps cdc21, anticorps CDC21, anticorps CDC54, anticorps NKCD, anticorps NKGCD, anticorps P1-CDC21, anticorps hCdc21, anticorps 19G, anticorps AI325074, anticorps AU045576, anticorps Cdc21, anticorps Mcmd4, anticorps mKIAA4003, anticorps mcdc21, anticorps cb1025, anticorps fc12c09, anticorps fj85g09, anticorps hm:zeh1616, anticorps wu:fc12c09, anticorps wu:fj85g09, anticorps zeh1616, anticorps minichromosome maintenance complex component 4 L homeolog, anticorps minichromosome maintenance complex component 4 S homeolog, anticorps minichromosome maintenance complex component 4, anticorps mcm4.L, anticorps mcm4.S, anticorps MCM4, anticorps mcm4, anticorps Mcm4
- Sujet
- The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 6 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of this protein by CDC2 kinase reduces the DNA helicase activity and chromatin binding of the MCM complex. This gene is mapped to a region on the chromosome 8 head-to-head next to the PRKDC/DNA-PK, a DNA-activated protein kinase involved in the repair of DNA double-strand breaks. Alternatively spliced transcript variants encoding the same protein have been reported.
- Poids moléculaire
- 97 kDa
- ID gène
- 4173
- UniProt
- P33991
- Pathways
- Réparation de l'ADN, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA
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