PAI1 anticorps (AA 188-216)
Aperçu rapide pour PAI1 anticorps (AA 188-216) (ABIN5535643)
Antigène
Voir toutes PAI1 (SERPINE1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 188-216
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Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogène
- This SERPINE1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 188-216 amino acids from the Central region of human SERPINE1.
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Isotype
- Ig Fraction
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Indications d'application
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For WB starting dilution is: 1:1000
For FACS starting dilution is: 1:10~50 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Supplied in PBS with 0.09 % (W/V) sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- PAI1 (SERPINE1) (Plasminogen Activator Inhibitor 1 (SERPINE1))
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Autre désignation
- SERPINE1
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Sujet
- This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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Poids moléculaire
- 45 kDa
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ID gène
- 5054
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UniProt
- P05121
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Pathways
- Signalisation p53, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagy, Smooth Muscle Cell Migration
Antigène
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