ERI2 anticorps (AA 444-472)

N° du produit ABIN5536072

Cet anticorps anti-ERI2 Polyclonal Lapin (ABIN5536072) détecte spécifiquement ERI2 dans WB. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour ERI2 anticorps (AA 444-472) (ABIN5536072)

Antigène: ERI2 (EXOD1) (ERI1 Exoribonuclease Family Member 2 (EXOD1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ERI2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-ERI2 anticorps

Épitope: AA 444-472

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This ERI2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 444-472 amino acids from the Central region of human ERI2.

Isotype: Ig Fraction

Information d'application

Indications d'application: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur ERI2

Antigène: ERI2 (EXOD1) (ERI1 Exoribonuclease Family Member 2 (EXOD1))

Autre désignation: ERI2

Sujet: EXOD1 (Exonuclease domain-containing protein 1), also known as ERI2 (ERI1 exoribonuclease 2), is a 691 amino acid protein that contains one exonuclease domain, which catalyzes the hydrolysis of unpaired or mismatched nucleotides. EXOD1 acitivity is dependent on the binding of two magnesium ions per subunit. There are four isoforms of EXOD1 that are produced as a result of alternative splicing events. The gene encoding EXOD1 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3 % of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.

Poids moléculaire: 77 kDa

ID gène: 112479

UniProt: A8K979