SPG20 anticorps (C-Term)

N° du produit ABIN5537986

Cet anticorps anti-SPG20 est un anticorps Lapin Polyclonal détectant SPG20 dans WB. Adapté pour Humain.

Aperçu rapide pour SPG20 anticorps (C-Term) (ABIN5537986)

Antigène: SPG20 (Spastic Paraplegia 20 (Troyer Syndrome) (SPG20))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SPG20 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-SPG20 anticorps

Épitope: AA 491-519, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This SPG20 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 491-519 amino acids from the C-terminal region of human SPG20.

Isotype: Ig Fraction

Information d'application

Indications d'application: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur SPG20

Antigène: SPG20 (Spastic Paraplegia 20 (Troyer Syndrome) (SPG20))

Autre désignation: SPG20

Sujet: SPG20 is a protein containing a MIT (Microtubule Interacting and Trafficking molecule) domain, and is implicated in regulating endosomal trafficking and mitochondria function. The protein localizes to mitochondria and partially co-localizes with microtubules. Stimulation with epidermal growth factor (EGF) results in protein translocation to the plasma membrane, and the protein functions in the degradation and intracellular trafficking of EGF receptor. Multiple alternatively spliced variants, encoding the same protein, have been identified. Mutations associated with this gene cause autosomal recessive spastic paraplegia 20 (Troyer syndrome).

Poids moléculaire: 73 kDa

ID gène: 23111

UniProt: Q8N0X7

Pathways: Regulation of Cell Size, SARS-CoV-2 Protein Interactome