SPG20 anticorps (C-Term)
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- Antigène Voir toutes SPG20 Anticorps
- SPG20 (Spastic Paraplegia 20 (Troyer Syndrome) (SPG20))
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Épitope
- AA 491-519, C-Term
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp SPG20 est non-conjugé
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Application
- Western Blotting (WB)
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogène
- This SPG20 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 491-519 amino acids from the C-terminal region of human SPG20.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product SPG20 Anticorps primaire
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- Indications d'application
- For WB starting dilution is: 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Supplied in PBS with 0.09 % (W/V) sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- Antigène
- SPG20 (Spastic Paraplegia 20 (Troyer Syndrome) (SPG20))
- Autre désignation
- SPG20 (SPG20 Produits)
- Synonymes
- anticorps SPARTIN, anticorps TAHCCP1, anticorps AI840044, anticorps C79168, anticorps mKIAA0610, anticorps spartin, anticorps Spg20, anticorps spg20a, anticorps zgc:172059, anticorps spg20b, anticorps zgc:153766, anticorps spartin, anticorps spastic paraplegia 20, spartin (Troyer syndrome) homolog (human), anticorps spartin a, anticorps spartin b, anticorps SPART, anticorps Spg20, anticorps Spart, anticorps sparta, anticorps spartb
- Sujet
- SPG20 is a protein containing a MIT (Microtubule Interacting and Trafficking molecule) domain, and is implicated in regulating endosomal trafficking and mitochondria function. The protein localizes to mitochondria and partially co-localizes with microtubules. Stimulation with epidermal growth factor (EGF) results in protein translocation to the plasma membrane, and the protein functions in the degradation and intracellular trafficking of EGF receptor. Multiple alternatively spliced variants, encoding the same protein, have been identified. Mutations associated with this gene cause autosomal recessive spastic paraplegia 20 (Troyer syndrome).
- Poids moléculaire
- 73 kDa
- ID gène
- 23111
- UniProt
- Q8N0X7
- Pathways
- Regulation of Cell Size, SARS-CoV-2 Protein Interactome
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