Chromogranin A anticorps
Aperçu rapide pour Chromogranin A anticorps (ABIN5540207)
Antigène
Voir toutes Chromogranin A (CHGA) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- Recognizes Chromogranin A (CGA).
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Purification
- Affinity Chromatography on Protein G.
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Immunogène
- Genetic immunisation with cDNA encoding CGA
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Isotype
- IgG1
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Indications d'application
- Flow cytometry: 1.2 μg/10e6 cells. ELISA: 1/200-1/400. Cell based ELISA with intakt, transiently transfected cells: 1/200-1/400.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Phosphate buffered saline, pH 7.2
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
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Date de péremption
- 12 months
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- Chromogranin A (CHGA)
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Autre désignation
- chromogranin a
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Sujet
- Chromogranin A (CgA) is a 49 kDa protein which is a member of the granin/secretogranin family of acidic glycoproteins. It is specifically expressed in all endocrine and neuroendocrine cells and plays multiple roles in the process of regulated secretion of peptide hormones and neurotransmitters (1). Owing to its over-expression in several tumors of neuroendocrine origin, CgA is of diagnostic value in classical endocrine, in hormone-negative and in neuroendocrine tumors (2).
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UniProt
- P10645
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Pathways
- Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling
Antigène
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