Complement Factor I anticorps

N° du produit ABIN5540272

Cet anticorps anti-Complement Factor I Monoclonal Souris (Clone OX-21) (ABIN5540272) détecte spécifiquement Complement Factor I dans WB, IP, FACS, EIA, RIA et IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Complement Factor I anticorps (ABIN5540272)

Antigène: Complement Factor I (CFI)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Complement Factor I est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Flow Cytometry (FACS), Enzyme Immunoassay (EIA), Radioimmunoassay (RIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: OX-21

Détail du produit anti-Complement Factor I anticorps

Specificité: This monoclonal antibody clone OX-21 recognizes Human Complement Protein Factor I. Factor I has two polypeptide chains, 56kD and 38kD. This antibody detects only the 56kD chain. This clone has been reported not to cross react with Rat. Species: Human.

Purification: Protein G Chromatography

Immunogène: Purified Human Complement Factor 1. Spleen cells from immunised FI cross DBA/2 x Balb/c mice were fused with cells of the NS-1 mouse myeloma cell line.

Isotype: IgG1

Information d'application

Indications d'application: ELISA. Titre: 1/40 000 (plates coated with 2 μg/mL purified Factor I and HRPO Goat anti-Mouse IgG secondary antibody). Western Blot. Flow Cytometry. Immunoprecipitation. Immunohistochemistry on Paraffin Sections (20 μg/mL).

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS Preservatives: 0.02 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur Complement Factor I

Antigène: Complement Factor I (CFI)

Autre désignation: complement factor i

Sujet: Factor I is a plasma protein of molecular weight 88 kDa, consisting of two disulphide linked chains of 50 and 38 kDa. Factor I is a serine protease with a high degree of specificity for C3b and C4b. It has a requirement for protein cofactors for cleavage of these complement proteins, Factor H, CR1 or MCP are required for C3b cleavage and C4bp or CR1 for C4b cleavage.

UniProt: P05156

Pathways: Système du Complément