GFRA2 anticorps
Aperçu rapide pour GFRA2 anticorps (ABIN5540353)
Antigène
Voir toutes GFRA2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Specificité
- This antibody detects Human GFRa-2 and doesn't cross-react with hGFRa-1, hGFRa-3, hGFRa-4. Other species not tested.
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Purification
- Affinity Chromatography
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Immunogène
- Recombinant His-tagged human GFRa-2 protein produced using CHO-based. For production of hGFRa-2, glycosylphosphatidyl-inositol GPI-anchor was removed and protein was secreted to the cell culture supernatant. Protein was purified by Ni-affinity chromatography following gel-filtration from cell culture supernatant.
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Isotype
- IgY
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Indications d'application
- ELISA: 1/128000-1/160000. Western blot: 1/5000-1/10000. Immunofluorescence: 1/500-1/1000.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Concentrated Ammonium Sulphate in PBS pH 7.4
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Stock
- 4 °C
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Stockage commentaire
- Upon receipt, store at 2-8°C. As product is (NH4) 2 SO 4 precipitate, mix well by pipetting or vortexing prior use. Shelf life: One year from despatch.
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- GFRA2 (GDNF Family Receptor alpha 2 (GFRA2))
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Autre désignation
- gfra2,gdnfr-beta
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Sujet
- Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The GFRa-1 is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol (GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor (www.ncbi.nlm.nih.gov/gene/2674).
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UniProt
- O00451
Antigène
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