IL9 Receptor anticorps

N° du produit ABIN5540440

Cet anticorps anti-IL9 Receptor est un anticorps Souris Monoclonal détectant IL9 Receptor dans FACS, Func et EIA. Adapté pour Humain.

Aperçu rapide pour IL9 Receptor anticorps (ABIN5540440)

Antigène: IL9 Receptor (IL9R) (Interleukin 9 Receptor (IL9R))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IL9 Receptor est non-conjugé

Application: Flow Cytometry (FACS), Functional Studies (Func), Enzyme Immunoassay (EIA)

Clone: AH9R7

Détail du produit anti-IL9 Receptor anticorps

Specificité: This antibody recognizes CD129 / IL-9R alpha, a 57 kDa type I transmembrane glycoprotein expressed at low levels by lymphocytes, blood cell progenitors, eosinophils, mast cells, epithelial cells, muscle cells and neurons.

Purification: Protein-A affinity chromatography (> 95% pure by SDS-PAGE)

Immunogène: Human CD129-transfected cell line

Isotype: IgG2b

Information d'application

Indications d'application: Flow cytometry: Use bright fluorochromes or signal multiplying detection. ELISA. Functional application: blocking.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 95 % pure by SDS-PAGE) Buffer System: Phosphate buffered saline (PBS) Preservatives: 15 mM sodium azide, approx. pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store undiluted at 2-8°C. DO NOT FREEZE! Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur IL9 Receptor

Antigène: IL9 Receptor (IL9R) (Interleukin 9 Receptor (IL9R))

Autre désignation: cd129,il9r

Sujet: CD129 serves as the high affinity alpha subunit of IL-9 receptor. It associates with CD132, the common gamma chain shared by receptors of many different cytokines. CD129 is expressed at low levels by T and B cells, blood cell progenitors, eosinophils, mast cells, epithelial cells, muscle cells and neurons. Its signaling (through JAK/STAT pathways) results in proliferative and anti-apoptotic response, which is critical e.g. for intrathymic T cell development and survival of various cell types. The gene for CD129 is located at the pseudoautosomal regions of X and Y chromosomes and it may be related with the development of asthma.

UniProt: Q01113

Pathways: Signalistation JAK/STAT, Growth Factor Binding