IL9 Receptor anticorps

N° du produit ABIN5540440

Cet anticorps anti-IL9 Receptor Monoclonal Souris (Clone AH9R7) (ABIN5540440) détecte spécifiquement IL9 Receptor dans FACS, Func et EIA. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour IL9 Receptor anticorps (ABIN5540440)

Antigène: IL9 Receptor (IL9R) (Interleukin 9 Receptor (IL9R))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IL9 Receptor est non-conjugé

Application: Flow Cytometry (FACS), Functional Studies (Func), Enzyme Immunoassay (EIA)

Clone: AH9R7

Détail du produit anti-IL9 Receptor anticorps

Specificité: This antibody recognizes CD129 / IL-9R alpha, a 57 kDa type I transmembrane glycoprotein expressed at low levels by lymphocytes, blood cell progenitors, eosinophils, mast cells, epithelial cells, muscle cells and neurons.

Purification: Protein-A affinity chromatography (> 95% pure by SDS-PAGE)

Immunogène: Human CD129-transfected cell line

Isotype: IgG2b

Information d'application

Indications d'application: Flow cytometry: Use bright fluorochromes or signal multiplying detection. ELISA. Functional application: blocking.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 95 % pure by SDS-PAGE) Buffer System: Phosphate buffered saline (PBS) Preservatives: 15 mM sodium azide, approx. pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store undiluted at 2-8°C. DO NOT FREEZE! Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur IL9 Receptor

Antigène: IL9 Receptor (IL9R) (Interleukin 9 Receptor (IL9R))

Autre désignation: cd129,il9r

Sujet: CD129 serves as the high affinity alpha subunit of IL-9 receptor. It associates with CD132, the common gamma chain shared by receptors of many different cytokines. CD129 is expressed at low levels by T and B cells, blood cell progenitors, eosinophils, mast cells, epithelial cells, muscle cells and neurons. Its signaling (through JAK/STAT pathways) results in proliferative and anti-apoptotic response, which is critical e.g. for intrathymic T cell development and survival of various cell types. The gene for CD129 is located at the pseudoautosomal regions of X and Y chromosomes and it may be related with the development of asthma.

UniProt: Q01113

Pathways: Signalistation JAK/STAT, Growth Factor Binding