NCOA1 anticorps (pSer75)

N° du produit ABIN5540512

Cet anticorps anti-NCOA1 Polyclonal Lapin (ABIN5540512) détecte spécifiquement NCOA1 dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour NCOA1 anticorps (pSer75) (ABIN5540512)

Antigène: NCOA1 (Nuclear Receptor Coactivator 1 (NCOA1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NCOA1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-NCOA1 anticorps

Épitope: pSer75

Specificité: The antibody detects endogenous level of Src only when phosphorylated at serine 75.

Purification: Affinity chromatography using epitope-specific peptide

Immunogène: Peptide sequence around phosphorylation site of serine 75 (V-T-S(p)-P-Q) derived from Human Src (KLH-conjugated)

Information d'application

Indications d'application: Western blot: 1:500~1:1000.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Upon receipt, store undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur NCOA1

Antigène: NCOA1 (Nuclear Receptor Coactivator 1 (NCOA1))

Autre désignation: src1

Sujet: Proto-oncogenic cytoplasmic tyrosine kinase of the SRC family. Highly expressed in certain fully differentiated cells such as neurons, platelets and macrophages. Phosphorylation of an activation loop tyrosine activates the enzyme phosphorylation of a tyrosine in the C-terminus by Csk inhibits the enzyme.

UniProt: P12931

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha