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SYN1 anticorps

L’anticorps Lapin Polyclonal anti-SYN1 a été validé pour WB, IF, ICC et IP. Il convient pour détecter SYN1 dans des échantillons de Humain, Rat, Souris et Boeuf (Vache).
N° du produit ABIN5540676

Aperçu rapide pour SYN1 anticorps (ABIN5540676)

Antigène

Voir toutes SYN1 Anticorps
SYN1 (Synapsin I (SYN1))

Reactivité

  • 109
  • 87
  • 65
  • 14
  • 5
  • 4
  • 2
  • 2
  • 2
  • 1
  • 1
Humain, Rat, Souris, Boeuf (Vache)

Hôte

  • 118
  • 8
Lapin

Clonalité

  • 109
  • 17
Polyclonal

Conjugué

  • 79
  • 6
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp SYN1 est non-conjugé

Application

  • 91
  • 47
  • 42
  • 20
  • 13
  • 13
  • 10
  • 10
  • 9
  • 7
  • 3
  • 2
  • 2
  • 2
  • 1
Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunoprecipitation (IP)
  • Specificité

    Specific for the ~78k synapsin I doublet in Western blots of rat brain extracts. Immunolabeling blocked by preadsorption of antibody with the protein used to generate the antibody.

    Purification

    Affinity purification using a column to which the native protein was coupled

    Immunogène

    Native protein purified from bovine brain

    Isotype

    Ig Fraction
  • Indications d'application

    Western blot: 1/1000. Immunohistochemistry / immunoflourescence: 1:1000. Immunoprecipitation: 2 μL per 200 μg lysate.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    100 μL in 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg BSA per ml and 50 % glycerol

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

    Date de péremption

    12 months
  • Antigène

    SYN1 (Synapsin I (SYN1))

    Autre désignation

    synapsin-1

    Sujet

    Synapsin I plays a key role in synaptic plasticity in brain (Feng et al., 2002 Nayak et al., 1996). This effect is due in large part to the ability of the synapsins to regulate the availability of synaptic vesicles for release. In addition to its role in plasticity, the expression of synapsin I is a precise indicator of synapse formation (Moore and Bernstein, 1989 Stone et al., 1994). Thus, synapsin I immunocytochemistry provides a valuable tool for the study of synaptogenesis. The role of synapsin in synaptic plasticity and in synaptogensis is regulated by phosphorylation (Jovanovic et al., 2001 Kao et al., 2002).

    UniProt

    P17599
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