TERT anticorps (AA 627-656)

N° du produit ABIN5540961

L’anticorps Lapin Polyclonal anti-TERT a été validé pour WB, FACS, IF, ICC et IHC (p). Il convient pour détecter TERT dans des échantillons de Humain.

Aperçu rapide pour TERT anticorps (AA 627-656) (ABIN5540961)

Antigène: TERT (Telomerase Reverse Transcriptase (TERT))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TERT est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-TERT anticorps

Épitope: AA 627-656

Specificité: This antibody detects Human TERT at center. Other species not tested.

Purification: Ammonium Sulfate Precipitation

Immunogène: KLH conjugated synthetic peptide selected from the Center region of Human TERT.

Information d'application

Indications d'application: Immunofluorescence: 1/10-1/50. Western blot: 1/1000, Flow Cytometry: 1/10-1/50. Immunohistochemistry on Paraffin Sections: 1/100.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS Preservatives: 0.09 % (W/V) Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur TERT

Antigène: TERT (Telomerase Reverse Transcriptase (TERT))

Autre désignation: tert

Sujet: Telomerase is a ribonucleoprotein polymerase that maintains telomere ends by addition of the telomere repeat TTAGGG. The enzyme consists of a protein component with reverse transcriptase activity, encoded by this gene, and an RNA component which serves as a template for the telomere repeat. Telomerase expression plays a role in cellular senescence, as it is normally repressed in postnatal somatic cells resulting in progressive shortening of telomeres. Deregulation of telomerase expression in somatic cells may be involved in oncogenesis. Studies in mouse suggest that telomerase also participates in chromosomal repair, since de novo synthesis of telomere repeats may occur at double-stranded breaks.

UniProt: O14746

Pathways: Telomere Maintenance