CBX3 anticorps

N° du produit ABIN5540964

L’anticorps Souris Monoclonal anti-CBX3 a été validé pour IHC (p). Il convient pour détecter CBX3 dans des échantillons de Humain, Souris et Porc.

Aperçu rapide pour CBX3 anticorps (ABIN5540964)

Antigène: CBX3 (Chromobox Homolog 3 (CBX3))

Reactivité: Humain, Souris, Porc

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CBX3 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 2MOD-1G6

Détail du produit anti-CBX3 anticorps

Specificité: This antibody detects HP1γ.

Purification: Purified

Immunogène: Recombinant mouse HP1gamma

Isotype: IgG1

Information d'application

Indications d'application: Immunohistochemistry on paraffin sections: 0.4 μg/mL (1/500). Suggested positive control: Human / Porcine brain cortex.

Restrictions: For Research Use only

Stockage

Buffer: Buffer System: Phosphate buffered saline pH 7.2 (PBS) Preservatives: 0.01 % Kathon Stabilizers: 5 mg/mL bovine serum albumin (BSA)

Stock: 4 °C,-20 °C

Stockage commentaire: Store lyophilized at 2-8°C for 6 month or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur CBX3

Antigène: CBX3 (Chromobox Homolog 3 (CBX3))

Autre désignation: cbx3

Sujet: Heterochromatin Protein 1 (HP1) (Chromobox Homolog, CBX) includes three isoforms in mammals, designated α, β, and γ. HP1 proteins are approximately 25 kDa in size. They are highly conserved adapter proteins with important regulatory functi ons in the cell nucleus. These functions include notably gene silencing by heterochromatin formation. HP1 proteins are fundamental units of heterochromatin packaging that are enriched at the centromeres and telomeres of nearly all Eukaryotic chromosomes. HP1β and γ also localize to euchromatic sites in the genome. Members of the HP1 family are characterized by an N-terminal chromodomain and a C-terminal chromoshadow domain, separated by a Hinge region. Chromodomain and chromoshadow domain establish secondary interactions with a large number of other proteins. HP1 proteins are subject to multiple types of post-translational modifications, including phosphorylation, acetylation, methylation, ubiquitination and sumoylation, suggesting multiple means of regulation.

UniProt: P23198