BCL2L1 anticorps (pThr115)

N° du produit ABIN5541071

Cet anticorps Lapin Polyclonal détecte spécifiquement BCL2L1 dans EIA. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour BCL2L1 anticorps (pThr115) (ABIN5541071)

Antigène: BCL2L1 (BCL2-Like 1 (BCL2L1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BCL2L1 est non-conjugé

Application: Enzyme Immunoassay (EIA)

Détail du produit anti-BCL2L1 anticorps

Épitope: pThr115

Séquence: TSQLHITpPG TAY

Specificité: This antibody detects Human and other species with consensus Bcl-xL peptide (TSQLHITpPGTAY).

Purification: Protein G affinity

Immunogène: A synthetic peptide derived from Threonine 115 phosphorylated Bcl-xL, conjugated with KLH

Information d'application

Indications d'application: ELISA: The antibody, when 1:10,000 1:100,000 diluted, can detect the Threonine 115 phosphorylated Bcl-xL coated on ELISA plate.

Restrictions: For Research Use only

Stockage

Buffer: 0.01M PBS, pH 7.4

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store lyophilized at 2-8°C for 6 month or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur BCL2L1

Antigène: BCL2L1 (BCL2-Like 1 (BCL2L1))

Autre désignation: bcl-2-like 1

Sujet: Bcl-xL is a prosurvival factor in the Bcl-2 family. It is a mitochondrial outer membrane protein that regulates the voltage-dependent anion channels (VDAC), and controls the production of reactive oxygen species and the release of cytochrome C. Bcl-xL gene knock-out resulted in embryonic lethality in animal model due to neuronal apoptosis and erythroid apoptosis. Bcl-xL is believed to be involved with the survival and differentiation of erythroid cells, iron metabolism and hemoglobin synthesis.

Pathways: Apoptose, Negative Regulation of intrinsic apoptotic Signaling