CTLA4 anticorps (AA 36-161)

N° du produit ABIN5541119

Cet anticorps Souris Monoclonal détecte spécifiquement CTLA4 dans FACS, WB, ICC, IF et EIA. Il présente une réactivité envers Humain.

Aperçu rapide pour CTLA4 anticorps (AA 36-161) (ABIN5541119)

Antigène: CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CTLA4 est non-conjugé

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Clone: AT4F2

Détail du produit anti-CTLA4 anticorps

Épitope: AA 36-161

Specificité: This antibody detects CTLA4 at aa 36-161.

Purification: Protein-A affinity chromatography

Immunogène: Recombinant human CTLA4 (36-161aa) purified from E. coli

Isotype: IgG1

Information d'application

Indications d'application: ELISA. Western blot: Recommended starting dilution is 1:3000. Immunocytochemistry / Immunoflourescence. Flow cytometry.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.4 containing 0.02 % Sodium Azide and 10 % Glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur CTLA4

Antigène: CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))

Autre désignation: cd152,ctla4

Sujet: CTLA4 (Cytotoxic T-Lymphocyte Antigen 4), also known as CD152, is a protein receptor that downregulates the immune system. CTLA4 is expressed on the surface of Helper T cells and transmits an inhibitory signal to T cells. CTLA4 is similar to the T-cell co-stimulatory protein, CD28, and both molecules bind to CD80 and CD86, also called B7-1 and B7-2 respectively, on antigen-presenting cells. CTLA4 transmits an inhibitory signal to T cells, whereas CD28 transmits a stimulatory signal. Mutations in CTLA4 have been associated with insulin-dependent diabetes mellitus, Graves' disease, Hashimoto's thyroiditis, celiac disease and other autoimmune diseases.

UniProt: P16410

Pathways: Cancer Immune Checkpoints