MAPT anticorps

N° du produit ABIN5541353

Cet anticorps Poulet Polyclonal détecte spécifiquement MAPT dans WB, IF, ICC et IHC (fro). Il présente une réactivité avec des échantillons de Humain et Rat.

Aperçu rapide pour MAPT anticorps (ABIN5541353)

Antigène: MAPT (Microtubule-Associated Protein tau (MAPT))

Reactivité: Humain, Rat

Hôte: Poulet

Clonalité: Polyclonal

Conjugué: Cet anticorp MAPT est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-MAPT anticorps

Specificité: Specific for the ~48, 65 & 75 kDa Tau isoforms.

Purification: Ig Fraction

Immunogène: Recombinant full length Human Tau expressed in and purified from E. coli.

Isotype: Ig Fraction

Information d'application

Indications d'application: Western blotting: 1/10,000. Immunohistochemistry. Immunofluorescence: 1/1000.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservatives: 10 mM Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store the antibody undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur MAPT

Antigène: MAPT (Microtubule-Associated Protein tau (MAPT))

Autre désignation: mapt,tau

Sujet: Tau is a key microtubule-associated protein that plays an important role in the formation of microtubules in axons (Binder et al. 1985). Six tau isoforms have been identified as products of a single gene produced by alternative mRNA splicing (Goedert 1990). Tau mutations have been implicated in many neurodegenerative disorders such as Alzheimer's disease (AD), Pick's disease and progressive supranuclear palsy.

UniProt: P10636

Pathways: Signalisation MAPK, Dynamique des Microtubules, M Phase, Regulation of Cell Size