ACE2 anticorps (C-Term, Extracellular Domain)

N° du produit ABIN5541562

Cet anticorps anti-ACE2 est un anticorps Souris Monoclonal détectant ACE2 dans WB et IHC (p). Adapté pour Humain.

Aperçu rapide pour ACE2 anticorps (C-Term, Extracellular Domain) (ABIN5541562)

Antigène: ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ACE2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 11A31

Détail du produit anti-ACE2 anticorps

Épitope: C-Term, Extracellular Domain

Specificité: This antibody was selected for its ability to detect ACE-2. Species: Human.

Purification: Affinity Chromatography on Protein G

Immunogène: Human ACE-2 recombinant protein (extracellular domain).

Isotype: IgG1

Information d'application

Indications d'application: Western Blot: 1/500-1/1000. Immunohistochemistry on Paraffin Sections: 1/50-1/200.

Restrictions: For Research Use only

Stockage

Buffer: Sterile PBS

Stock: 4 °C,-20 °C

Stockage commentaire: Store lyophilized at 2-8°C for 6 months or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur ACE2

Antigène: ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))

Autre désignation: ace2

Sujet: The protein encoded by the gene ACE belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63.

UniProt: Q9BYF1

Pathways: ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour