PAI1 anticorps

N° du produit ABIN5541683

Cet anticorps Souris Monoclonal détecte spécifiquement PAI1 dans WB, FACS, IHC (p) et EIA. Il présente une réactivité envers Humain.

Aperçu rapide pour PAI1 anticorps (ABIN5541683)

Antigène: PAI1 (SERPINE1) (Plasminogen Activator Inhibitor 1 (SERPINE1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PAI1 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Clone: 1D5

Détail du produit anti-PAI1 anticorps

Specificité: This antibody recognizes Human SERPINE1 / PAI-1. Other species not tested.

Purification: Purified

Immunogène: Purified recombinant fragment of Human SERPINE1 expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: ELISA : 1/10000. Western Blot: 1/500-1/2000. Flow Cytometry: 1/200-1/400. Immunohistochemistry on Paraffin Sections : 1/200-1/1000.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Buffer System: PBS Preservatives: 0.05 % Sodium Azide Stabilizers: 0.5 % BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur PAI1

Antigène: PAI1 (SERPINE1) (Plasminogen Activator Inhibitor 1 (SERPINE1))

Autre désignation: serpine1,pai1

Sujet: This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

UniProt: P05121

Pathways: Signalisation p53, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagy, Smooth Muscle Cell Migration