Fascin anticorps (AA 1-493)

N° du produit ABIN5541826

Cet anticorps anti-Fascin est un anticorps Souris Monoclonal détectant Fascin dans WB, FACS, IF, ICC et EIA. Adapté pour Humain.

Aperçu rapide pour Fascin anticorps (AA 1-493) (ABIN5541826)

Antigène: Fascin (FSCN1)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Fascin est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunocytochemistry (ICC), Enzyme Immunoassay (EIA)

Clone: AT13D2

Détail du produit anti-Fascin anticorps

Épitope: AA 1-493

Purification: Protein-A affinity chromatography

Immunogène: Recombinant human FSCN1 (1-493aa) purified from E. coli.

Isotype: IgG2b

Information d'application

Indications d'application: The antibody has been tested by ELISA, Western blot analysis, ICC/IF and Flow cytometry to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. In Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur Fascin

Antigène: Fascin (FSCN1)

Autre désignation: fascin

Sujet: FSCN1 is an actin-bundling protein that provides rigidity to filopodial bundles to efficiently push the membrane forward during cytoskeleton remodeling and cell migration. Probably involved in the assembly of actin filament bundles present in microspikes, membrane ruffles, and stress fibers. And this protein is absent from most normal epithelia yet is upregulated in multiple forms of human carcinoma, where its expression correlates clinically with a poor prognosis. FSCN1 expression has been localized to neurons, glial cells, and endothelial cells.

UniProt: Q16658