LGR4 anticorps

N° du produit ABIN5541954

L’anticorps Rat Monoclonal anti-LGR4 a été validé pour FACS et EIA. Il convient pour détecter LGR4 dans des échantillons de Humain et Souris.

Aperçu rapide pour LGR4 anticorps (ABIN5541954)

Antigène: LGR4 (Leucine-Rich Repeat Containing G Protein-Coupled Receptor 4 (LGR4))

Reactivité: Humain, Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp LGR4 est non-conjugé

Application: Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Clone: BBX-3A8

Détail du produit anti-LGR4 anticorps

Specificité: Recognizes LGR4 / GPR48. Selection: Based on recognition of the complete native protein expressed on transfected mammalian cells.

Purification: Affinity Chromatography on Protein G

Immunogène: cDNA encoding Human LGR4

Isotype: IgG2a

Information d'application

Indications d'application: Flow cytometry: 1.2 μg/10 6 cells. Cell based ELISA with intakt, transiently transfected cells: 1/200-1/400.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.2

Stock: 4 °C,-20 °C

Stockage commentaire: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur LGR4

Antigène: LGR4 (Leucine-Rich Repeat Containing G Protein-Coupled Receptor 4 (LGR4))

Autre désignation: lgr4,gpr48

Sujet: LGR4 (Leucine-rich repeat- containing G protein-coupled receptor 4) belongs to the superfamily of G protein-coupled receptors (GPCRs). It is a 951 amino acid multi-pass membrane protein and has multiple N-terminal leucine-rich repeats, which are important for interaction with the glycoprotein ligands, and 7 transmembrane domains (1,3). LGR4 is highly expressed in the adult human pancreas but also with moderate levels of expression in placenta, kidney, brain and heart (2). LGR4 functions as an orphan receptor that may be involved in physiologic activities throughout the cell. It is overexpressed in various cancer types and is thought to enhance carcinoma invasiveness and metastasis, suggesting an important role in tumor progression.

UniProt: Q9BXB1