PARK7/DJ1 anticorps

N° du produit ABIN5542008

L’anticorps Souris Monoclonal anti-PARK7/DJ1 a été validé pour WB, ICC et IF. Il convient pour détecter PARK7/DJ1 dans des échantillons de Humain, Souris, Rat et Boeuf (Vache).

Aperçu rapide pour PARK7/DJ1 anticorps (ABIN5542008)

Antigène: PARK7/DJ1 (PARK7) (Parkinson Protein 7 (PARK7))

Reactivité: Humain, Souris, Rat, Boeuf (Vache)

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PARK7/DJ1 est non-conjugé

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)

Clone: 4H4

Détail du produit anti-PARK7/DJ1 anticorps

Specificité: This antibody is specific for the ~21k park7 protein.

Purification: Affinity Chromatography

Immunogène: Full length recombinant human park7 expressed in and purified from E. coli.

Isotype: IgG1

Information d'application

Indications d'application: Western blotting: 1/2000. Immunofluorescence: 1/500.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS Preservatives: 10 mM Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store the antibody undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur PARK7/DJ1

Antigène: PARK7/DJ1 (PARK7) (Parkinson Protein 7 (PARK7))

Autre désignation: dj-1,park7

Sujet: Park7, also known as DJ-1, is a member of the peptidase C56 family of proteins and is thought to function as a molecular chaperone. Mutations in park7 have been associated with autosomal recessive, early onset Parkinson's disease (Bonifati et al., 2003). Recently, park7 has been shown to inhibit microtubule associated protein 1B aggregation thus leading to neuronal apoptosis (Wang et al., 2011).

UniProt: O88767

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Proton Transport