RAD18 anticorps (AA 332-430)
Aperçu rapide pour RAD18 anticorps (AA 332-430) (ABIN5542377)
Antigène
Voir toutes RAD18 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 332-430
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Fonction
- RAD18 Antibody
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Purification
- Purified antibody
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Immunogène
- Purified recombinant fragment of human RAD18 (AA: 332-430) expressed in E. Coli.
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Isotype
- IgG1
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Indications d'application
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ELISA: 1/10000
FCM: 1/200 - 1/400
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- RAD18 (E3 ubiquitin-protein ligase RAD18 (RAD18))
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Autre désignation
- RAD18
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Sujet
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The protein encoded by this gene is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6, which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA. Similar to its yeast counterpart, this protein is able to interact with the human homolog of yeast Rad6 protein through a conserved ring-finger motif. Mutation of this motif results in defective replication of UV-damaged DNA and hypersensitivity to multiple mutagens.
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Poids moléculaire
- 56.2 kDa
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ID gène
- 56852
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UniProt
- Q9NS91
Antigène
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