JARID2 anticorps (AA 1097-1246)
Aperçu rapide pour JARID2 anticorps (AA 1097-1246) (ABIN5542458)
Antigène
Voir toutes JARID2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 1097-1246
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Fonction
- JARID2 Antibody
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Purification
- Purified antibody
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Immunogène
- Purified recombinant fragment of human JARID2 (AA: 1097-1246) expressed in E. Coli.
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Isotype
- IgG2a
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Indications d'application
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- JARID2 (Jumonji, AT Rich Interactive Domain 2 (JARID2))
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Autre désignation
- JARID2
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Sujet
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This gene encodes a Jumonji- and AT-rich interaction domain (ARID)-domain-containing protein. The encoded protein is a DNA-binding protein that functions as a transcriptional repressor. This protein interacts with the Polycomb repressive complex 2 (PRC2) which plays an essential role in regulating gene expression during embryonic development. This protein facilitates the recruitment of the PRC2 complex to target genes. Alternate splicing results in multiple transcript variants. Mutations in this gene are associated with chronic myeloid malignancies.
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Poids moléculaire
- 139 kDa
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UniProt
- Q92833
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Pathways
- Chromatin Binding
Antigène
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