beta 2 Adrenergic Receptor anticorps (AA 302-413)

N° du produit ABIN5542567

Cet anticorps anti-beta 2 Adrenergic Receptor est un anticorps Souris Monoclonal détectant beta 2 Adrenergic Receptor dans WB, ELISA et FACS. Adapté pour Humain et Rat.

Aperçu rapide pour beta 2 Adrenergic Receptor anticorps (AA 302-413) (ABIN5542567)

Antigène: beta 2 Adrenergic Receptor (ADRB2) (Adrenergic, beta-2-, Receptor, Surface (ADRB2))

Reactivité: Humain, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp beta 2 Adrenergic Receptor est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Clone: 5G3B5

Détail du produit anti-beta 2 Adrenergic Receptor anticorps

Épitope: AA 302-413

Fonction: ADRB2 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human ADRB2 (AA: 302-413) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur beta 2 Adrenergic Receptor

Antigène: beta 2 Adrenergic Receptor (ADRB2) (Adrenergic, beta-2-, Receptor, Surface (ADRB2))

Autre désignation: ADRB2

Sujet: This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes.

Poids moléculaire: 46.5 kDa

ID gène: 154

UniProt: P07550

Pathways: cAMP Metabolic Process, Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Brown Fat Cell Differentiation