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CFHR5 anticorps (AA 344-569)

CFHR5 Reactivité: Humain WB, ELISA, FACS, IHC, ICC Hôte: Souris Monoclonal 3E1E10 unconjugated
N° du produit ABIN5542639
  • Antigène Voir toutes CFHR5 Anticorps
    CFHR5 (Complement Factor H-Related 5 (CFHR5))
    Épitope
    • 7
    • 6
    • 6
    • 6
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 344-569
    Reactivité
    • 36
    • 10
    Humain
    Hôte
    • 25
    • 11
    Souris
    Clonalité
    • 26
    • 10
    Monoclonal
    Conjugué
    • 16
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CFHR5 est non-conjugé
    Application
    • 26
    • 18
    • 15
    • 14
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunocytochemistry (ICC)
    Purification
    purified
    Immunogène
    Purified recombinant fragment of human CFHR5 (AA: 344-569) expressed in E. coli.
    Clone
    3E1E10
    Isotype
    IgG1
  • Indications d'application
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    4°C, -20°C for long term storage
  • Antigène
    CFHR5 (Complement Factor H-Related 5 (CFHR5))
    Autre désignation
    CFHR5 (CFHR5 Produits)
    Synonymes
    anticorps CFHL5, anticorps CFHR5D, anticorps FHR-5, anticorps FHR5, anticorps complement factor H related 5, anticorps CFHR5
    Sujet

    Description: This gene is a member of a small complement factor H (CFH) gene cluster on chromosome 1. Each member of this gene family contains multiple short consensus repeats (SCRs) typical of regulators of complement activation. The protein encoded by this gene has nine SCRs with the first two repeats having heparin binding properties, a region within repeats 5-7 having heparin binding and C reactive protein binding properties, and the C-terminal repeats being similar to a complement component 3 b (C3b) binding domain. This protein co-localizes with C3, binds C3b in a dose-dependent manner, and is recruited to tissues damaged by C-reactive protein. Allelic variations in this gene have been associated, but not causally linked, with two different forms of kidney disease: membranoproliferative glomerulonephritis type II (MPGNII) and hemolytic uraemic syndrome (HUS).,

    Aliases: FHR5, CFHL5, FHR-5, CFHR5D

    Poids moléculaire
    64.4 kDa
    ID gène
    81494
    HGNC
    81494
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