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CFHR5 anticorps (AA 450-569)

CFHR5 Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6138459
  • Antigène Voir toutes CFHR5 Anticorps
    CFHR5 (Complement Factor H-Related 5 (CFHR5))
    Épitope
    • 7
    • 6
    • 6
    • 6
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    AA 450-569
    Reactivité
    • 36
    • 10
    Humain
    Hôte
    • 24
    • 12
    Lapin
    Clonalité
    • 25
    • 11
    Polyclonal
    Conjugué
    • 16
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CFHR5 est non-conjugé
    Application
    • 26
    • 19
    • 16
    • 15
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Séquence
    GPPPSINNGD TTSFPLSVYP PGSTVTYRCQ SFYKLQGSVT VTCRNKQWSE PPRCLDPCVV SEENMNKNNI QLKWRNDGKL YAKTGDAVEF QCKFPHKAMI SSPPFRAICQ EGKFEYPICE
     Réactivité croisée
    Humain, Souris, Rat
    Attributs du produit
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogène
    Recombinant fusion protein containing a sequence corresponding to amino acids 450-569 of human CFHR5 (NP_110414.1).
    Isotype
    IgG
    Top Product
    Discover our top product CFHR5 Anticorps primaire
  • Indications d'application
    WB,1:500 - 1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    CFHR5 (Complement Factor H-Related 5 (CFHR5))
    Autre désignation
    CFHR5 (CFHR5 Produits)
    Synonymes
    anticorps CFHL5, anticorps CFHR5D, anticorps FHR-5, anticorps FHR5, anticorps complement factor H related 5, anticorps CFHR5
    Sujet
    This gene is a member of a small complement factor H (CFH) gene cluster on chromosome 1. Each member of this gene family contains multiple short consensus repeats (SCRs) typical of regulators of complement activation. The protein encoded by this gene has nine SCRs with the first two repeats having heparin binding properties, a region within repeats 5-7 having heparin binding and C reactive protein binding properties, and the C-terminal repeats being similar to a complement component 3 b (C3b) binding domain. This protein co-localizes with C3, binds C3b in a dose-dependent manner, and is recruited to tissues damaged by C-reactive protein. Allelic variations in this gene have been associated, but not causally linked, with two different forms of kidney disease: membranoproliferative glomerulonephritis type II (MPGNII) and hemolytic uraemic syndrome (HUS).,CFHR5,CFHL5,CFHR5D,FHR-5,FHR5,Immunology & Inflammation,Cell Intrinsic Innate Immunity Signaling Pathway,CFHR5
    Poids moléculaire
    64 kDa
    ID gène
    81494
    UniProt
    Q9BXR6
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