Complement C3c anticorps (AA 1521-1649)

N° du produit ABIN5542705

Cet anticorps anti-Complement C3c est un anticorps Souris Monoclonal détectant Complement C3c dans ELISA et IHC. Adapté pour Humain. Ce Primary Antibody a été cité dans 1 publication.

Aperçu rapide pour Complement C3c anticorps (AA 1521-1649) (ABIN5542705)

Antigène: Complement C3c (C3C) (Complement Component C3c (C3C))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Complement C3c est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Clone: 8B5H2

Détail du produit anti-Complement C3c anticorps

Épitope: AA 1521-1649

Fonction: C3C Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human C3C (AA: 1521-1649) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-Complement C3c (ABIN5542705)

Helsby, Leader, Fenn, Gulsen, Bryant, Doughton, Sharpe, Whitley, Caunt, James, Pope, Kelly, Chalmers: "CiteAb: a searchable antibody database that ranks antibodies by the number of times they have been cited." dans: BMC cell biology, Vol. 15, pp. 6, (2014) (PubMed).

Détails sur Complement C3c

Antigène: Complement C3c (C3C) (Complement Component C3c (C3C))

Autre désignation: C3C

Sujet: Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form the mature protein, which is then further processed to generate numerous peptide products. The C3a peptide, also known as the C3a anaphylatoxin, modulates inflammation and possesses antimicrobial activity. Mutations in this gene are associated with atypical hemolytic uremic syndrome and age-related macular degeneration in human patients.

Poids moléculaire: 187.1 kDa

ID gène: 718

UniProt: P01024