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Cyclin D3 anticorps

CCND3 Reactivité: Humain WB, IF (cc) Hôte: Lapin Monoclonal 4A8 unconjugated
N° du produit ABIN5557294
  • Antigène Voir toutes Cyclin D3 (CCND3) Anticorps
    Cyclin D3 (CCND3)
    Reactivité
    • 110
    • 46
    • 35
    • 16
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 95
    • 17
    Lapin
    Clonalité
    • 87
    • 25
    Monoclonal
    Conjugué
    • 52
    • 6
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Cyclin D3 est non-conjugé
    Application
    • 82
    • 34
    • 30
    • 26
    • 26
    • 20
    • 15
    • 15
    • 10
    • 8
    • 7
    • 5
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc))
     Réactivité croisée
    Humain
    Purification
    Purified by Protein A.
    Immunogène
    Recombinant human Cyclin D3 protein, around C-terminal 200aa.
    Clone
    4A8
    Isotype
    IgG
    Top Product
    Discover our top product CCND3 Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Antigène
    Cyclin D3 (CCND3)
    Autre désignation
    Cyclin D3 (CCND3 Produits)
    Synonymes
    anticorps zgc:103502, anticorps CCND3, anticorps 9230106B05Rik, anticorps AA682053, anticorps AL024085, anticorps AW146355, anticorps C78795, anticorps cyclin D3, anticorps ccnd3, anticorps CCND3, anticorps Ccnd3
    Sujet

    Synonyms: G1/S-specific cyclin-D3, CCND3

    Background: Regulatory component of the cyclin D3-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G(1)/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase. Hypophosphorylates RB1 in early G(1) phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. Also substrate for SMAD3, phosphorylating SMAD3 in a cell-cycle-dependent manner and repressing its transcriptional activity. Component of the ternary complex, cyclin D3/CDK4/CDKN1B, required for nuclear translocation and activity of the cyclin D-CDK4 complex.

    ID gène
    896
    UniProt
    P30281
    Pathways
    Cycle Cellulaire, Mitotic G1-G1/S Phases, Glycosaminoglycan Metabolic Process
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