Retinoblastoma 1 anticorps (pSer807)

N° du produit ABIN5557520

Cet anticorps anti-Retinoblastoma 1 est un anticorps Lapin Monoclonal détectant Retinoblastoma 1 dans WB et IF (cc). Adapté pour Humain, Souris et Rat.

Aperçu rapide pour Retinoblastoma 1 anticorps (pSer807) (ABIN5557520)

Antigène: Retinoblastoma 1 (RB1)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp Retinoblastoma 1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc))

Clone: 2D10

Détail du produit anti-Retinoblastoma 1 anticorps

Épitope: pSer807

Purification: Purified by Protein A.

Immunogène: Synthetic peptide derived from human Rb(S807), around 800-850aa (phospho S807).

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-2000
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Stock: -20 °C

Stockage commentaire: Store at -20°C

Date de péremption: 12 months

Détails sur Retinoblastoma 1

Antigène: Retinoblastoma 1 (RB1)

Autre désignation: Rb

Sujet:

Nuclear Marker.The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

Synonyms: RbSer780, OSRC, P105 RB, P105RB, PP105, PP110, pRb, RB 1, RB1, RB1 protein, Retinoblastoma 1 including osteosarcoma, Retinoblastoma 1, Retinoblastoma associated protein, Including osteosarcoma, Osteosarcoma, p105-Rb, Rb, RB_HUMAN, Retinoblastoma suspectibility protein, Retinoblastoma-associated protein, Retinoblastoma related osteosarcoma, Retinoblastoma susceptibility gene.

ID gène: 5925

UniProt: P06400

Pathways: Cycle Cellulaire, Intracellular Steroid Hormone Receptor Signaling Pathway, Mitotic G1-G1/S Phases, DNA Replication, Maintenance of Protein Location, Synthesis of DNA, Autophagy