CDK2 anticorps

N° du produit ABIN5557541

Cet anticorps anti-CDK2 est un anticorps Lapin Monoclonal détectant CDK2 dans WB et IHC (p). Adapté pour Souris et Rat.

Aperçu rapide pour CDK2 anticorps (ABIN5557541)

Antigène: CDK2 (Cyclin-Dependent Kinase 2 (CDK2))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp CDK2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 2E3

Détail du produit anti-CDK2 anticorps

Purification: Purified by Protein A.

Immunogène: Recombinant human Cdk2 protein, around C-terminal 100aa.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-5000
IHC-P 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Stock: -20 °C

Stockage commentaire: Store at -20°C

Date de péremption: 12 months

Détails sur CDK2

Antigène: CDK2 (Cyclin-Dependent Kinase 2 (CDK2))

Autre désignation: Cdk2

Sujet:

The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein kinase is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and essential for cell cycle G1/S phase transition. This protein associates with and regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Its activity is also regulated by its protein phosphorylation. Two alternatively spliced variants and multiple transcription initiation sites of this gene have been reported. [provided by RefSeq, Jul 2008].

Synonyms: CDKN2, p33(CDK2), Cyclin-dependent kinase 2, Cell division protein kinase 2, p33 protein kinase, CDK2

ID gène: 1017

UniProt: P24941

Pathways: Signalisation PI3K-Akt, Cycle Cellulaire, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA