BRP44 anticorps
Aperçu rapide pour BRP44 anticorps (ABIN5564218)
Antigène
Voir toutes BRP44 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- Recognizes endogenous human and mouse MPC-2.
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Réactivité croisée
- Humain, Souris
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Immunogène
- Peptide coupled to KLH.
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Isotype
- IgG2b
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- In PBS containing 25 % glycerol and 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C. -
Date de péremption
- 12 months
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- BRP44 (Brain Protein 44 (BRP44))
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Autre désignation
- MPC-2
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Sujet
- Pyruvate is the end-product of glycolysis, a major substrate for oxidative metabolism, and a branching point for glucose, lactate, fatty acid and amino acid synthesis. The mitochondrial enzymes that metabolize pyruvate are physically separated from cytosolic pyruvate pools and rely on a membrane transport system to shuttle pyruvate across the impermeable inner mitochondrial membrane (IMM). Two proteins, mitochondrial pyruvate carriers MPC-1 and MPC-2, form a heterooligomeric complex in the IMM to facilitate pyruvate transport. This step is required for mitochondrial pyruvate oxidation and carboxylation-critical reactions in intermediary metabolism that are dysregulated in several common metabolic diseases.
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Pathways
- L'effet Warburg
Antigène
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