BRP44 anticorps

N° du produit ABIN5564218

Détail du produit anti-BRP44 anticorps

Antigène: BRP44 (Brain Protein 44 (BRP44))

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp BRP44 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Specificité: Recognizes endogenous human and mouse MPC-2.

Réactivité croisée: Humain, Souris

Immunogène: Peptide coupled to KLH.

Clone: JCM-1

Isotype: IgG2b

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: In PBS containing 25 % glycerol and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C.

Date de péremption: 12 months

Détails sur BRP44

Antigène: BRP44 (Brain Protein 44 (BRP44))

Autre désignation: MPC-2 (BRP44 Produits)

Synonymes: anticorps BRP44, anticorps 0610006C01Rik, anticorps 2010002I07Rik, anticorps 2610205H19Rik, anticorps AA108335, anticorps Brp44, anticorps ESTM43, anticorps brp44, anticorps wu:fb22b02, anticorps wu:fb22g07, anticorps zgc:56391, anticorps zgc:86614, anticorps MGC53394, anticorps DKFZp459F1815, anticorps RGD1563422, anticorps mitochondrial pyruvate carrier 2, anticorps mitochondrial pyruvate carrier 2 S homeolog, anticorps uncharacterized protein, anticorps MPC2, anticorps Mpc2, anticorps mpc2, anticorps mpc2.S, anticorps LOC706595, anticorps LOC100285678

Sujet: Pyruvate is the end-product of glycolysis, a major substrate for oxidative metabolism, and a branching point for glucose, lactate, fatty acid and amino acid synthesis. The mitochondrial enzymes that metabolize pyruvate are physically separated from cytosolic pyruvate pools and rely on a membrane transport system to shuttle pyruvate across the impermeable inner mitochondrial membrane (IMM). Two proteins, mitochondrial pyruvate carriers MPC-1 and MPC-2, form a heterooligomeric complex in the IMM to facilitate pyruvate transport. This step is required for mitochondrial pyruvate oxidation and carboxylation-critical reactions in intermediary metabolism that are dysregulated in several common metabolic diseases.

Pathways: L'effet Warburg