FIL1h anticorps

N° du produit ABIN5564285

Cet anticorps Souris Monoclonal détecte spécifiquement FIL1h dans WB et ELISA. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour FIL1h anticorps (ABIN5564285)

Antigène: FIL1h (Interleukin 1 eta (FIL1h))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp FIL1h est non-conjugé

Application: Western Blotting (WB), ELISA

Clone: Jacky-1

Détail du produit anti-FIL1h anticorps

Fonction: anti-IL-36beta (human), mAb (Jacky-1)

Specificité: Recognizes human IL-36beta. Does not cross-react with mouse IL-36beta and IL-36gamma.

Aucune reactivité croisée: Souris

Réactivité croisée (Details): Does not cross-react with mouse IL-36beta and IL-36gamma.

Attributs du produit: Monoclonal Antibody. Recognizes human IL-36beta. Does not cross-react with mouse IL-36beta and IL-36gamma. Isotype: Mouse IgG1kappa. Clone: Jacky-1. Applications: ELISA, WB. Liquid. In PBS containing 10 % glycerol and 0.02 % sodium azide. IL-36alpha (IL-1F6), IL-36beta (IL-1F8) and IL-36gamma (IL-1F9) bind to IL-36R (IL-1Rrp2) and IL-1RAcP, activating similar intracellular signals as IL-1. IL-36Ra inhibits the production of proinflammatory cytokines, including IL-12, IL-1beta, IL-6, TNF-alpha and IL-23 induced by IL-36 in BMDC and CD4 T cells. Skin and dendritic cells are targets of the IL-36 interleukins leading to a Th1 response. These cytokines may represent potential targets for immune-mediated inflammatory conditions or, alternatively, could be used as adjuvants in vaccination.

Pureté: >95 % (SDS-PAGE)

Immunogène: Recombinant human IL-36beta.

Isotype: IgG1 kappa

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: In PBS containing 10 % glycerol and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.

Stock: 4 °C,-20 °C

Stockage commentaire:

+4°C

-20°C

Stable for at least 1 year after receipt when stored at -20°C.

Date de péremption: 12 months

Détails sur FIL1h

Antigène: FIL1h (Interleukin 1 eta (FIL1h))

Autre désignation: IL-36beta

Sujet:

Alternate Names/Synonyms: Interleukin-36beta Interleukin-1 Family Member 8, IL-1F8

Product Description: IL-36alpha (IL-1F6), IL-36beta (IL-1F8) and IL-36gamma (IL-1F9) bind to IL-36R (IL-1Rrp2) and IL-1RAcP, activating similar intracellular signals as IL-1. IL-36Ra inhibits the production of proinflammatory cytokines, including IL-12, IL-1beta, IL-6, TNF-alpha and IL-23 induced by IL-36 in BMDC and CD4 T cells. Skin and dendritic cells are targets of the IL-36 interleukins leading to a Th1 response. These cytokines may represent potential targets for immune-mediated inflammatory conditions or, alternatively, could be used as adjuvants in vaccination.