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FIL1h anticorps

FIL1h Reactivité: Humain WB, ELISA Hôte: Souris Monoclonal Jacky-1 unconjugated
N° du produit ABIN5564285
  • Antigène Tous les produits FIL1h
    FIL1h (Interleukin 1 eta (FIL1h))
    Reactivité
    • 30
    • 1
    Humain
    Hôte
    • 25
    • 5
    Souris
    Clonalité
    • 27
    • 3
    Monoclonal
    Conjugué
    • 13
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp FIL1h est non-conjugé
    Application
    • 23
    • 18
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA
    Specificité
    Recognizes human IL-36beta.
     Réactivité croisée
    Humain
    Aucune reactivité croisée
    Souris
    Réactivité croisée (Details)
    Does not cross-react with mouse IL-36beta and IL-36gamma.
    Pureté
    >95 % (SDS-PAGE)
    Immunogène
    Recombinant human IL-36beta.
    Clone
    Jacky-1
    Isotype
    IgG1
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    In PBS containing 10 % glycerol and 0.02 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 1 year after receipt when stored at -20°C.
    Date de péremption
    12 months
  • Antigène
    FIL1h (Interleukin 1 eta (FIL1h))
    Autre désignation
    IL-36beta (FIL1h Produits)
    Synonymes
    anticorps 2310043N20Rik, anticorps Il36b, anticorps FIL1, anticorps FIL1-(ETA), anticorps FIL1H, anticorps FILI-(ETA), anticorps IL-1F8, anticorps IL-1H2, anticorps IL1-ETA, anticorps IL1F8, anticorps IL1H2, anticorps Il1f8, anticorps interleukin 1 family, member 8, anticorps interleukin 36 beta, anticorps interleukin 36, beta, anticorps Il1f8, anticorps IL36B, anticorps Il36b
    Sujet
    IL-36alpha (IL-1F6), IL-36beta (IL-1F8) and IL-36gamma (IL-1F9) bind to IL-36R (IL-1Rrp2) and IL-1RAcP, activating similar intracellular signals as IL-1. IL-36Ra inhibits the production of proinflammatory cytokines, including IL-12, IL-1beta, IL-6, TNF-alpha and IL-23 induced by IL-36 in BMDC and CD4 T cells. Skin and dendritic cells are targets of the IL-36 interleukins leading to a Th1 response. These cytokines may represent potential targets for immune-mediated inflammatory conditions or, alternatively, could be used as adjuvants in vaccination.
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