APOE anticorps

N° du produit ABIN5596681

N° du produit (Fournisseur): 600-101-197

Cet anticorps anti-APOE est un anticorps Chèvre Polyclonal détectant APOE dans WB, ELISA, IHC et IP. Adapté pour Humain et Rat. Ce Primary Antibody a été cité dans 1 publication.

Aperçu rapide pour APOE anticorps (ABIN5596681)

Antigène: APOE (Apolipoprotein E (APOE))

Reactivité: Humain, Rat

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp APOE est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Détail du produit anti-APOE anticorps

N° du produit (Fournisseur): 600-101-197

Fournisseur: Rockland

Fonction: APOLIPOPROTEIN E Antibody

Réactivité croisée (Details): Typically less than 1 % cross-reactivity against other types of apoLipoprotein was detected by ELISA against purified standards.

Attributs du produit: Synonyms: goat anti-Apolipoprotein E3 antibody, Alzheimer disease 2 antibody, Apo-E antibody, Apo E antibody, ApoE antibody, APOEA antibody, Apolipoprotein-E antibody, Apoprotein antibody

Purification: Anti-Apolipoprotein E has been prepared by immunoaffinity chromatography using immobilized antigens followed by extensive cross-adsorption against other apoLipoproteins and human serum proteins to remove any unwanted specificities.

Stérilité: Sterile filtered

Immunogène:

Immunogen: Apolipoprotein Type E was isolated from human plasma by density gradient centrifugation followed by HPLC purification.

Immunogen Type: Native Protein

Isotype: IgG

Information d'application

Indications d'application:

Immunohistochemistry Dilution: 1:50 - 1:200

Application Note: Apolipoprotein E antibodies have been tested by western blot and used for indirect trapping ELISA for quantitation of antigen in serum using a standard curve, for immunoprecipitation and for western blotting for highly sensitive qualitative analysis.

Western Blot Dilution: 1:500 - 1:2,000

Immunoprecipitation Dilution: 1:100

ELISA Dilution: 1:4,000 - 1:8,000

Other: User Optimized

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer:

Buffer: 0.125 M Sodium Borate, 0.075 M Sodium Chloride, 0.005 M EDTA, pH 8.0

Stabilizer: None

Preservative: 0.01 % (w/v) Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store vial at 4° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  Dilute only prior to immediate use.  For extended storage, mix with an equal volume of glycerol, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. 

Date de péremption: 12 months

Références pour anticorps anti-APOE (ABIN5596681)

Lu, Yuan, Wang, Zhang, Yuan, Wu, Zhou, He, Lu, Chen, Fan, Liang, Cheng: "Spontaneous severe hypercholesterolemia and atherosclerosis lesions in rabbits with deficiency of low-density lipoprotein receptor (LDLR) on exon 7." dans: EBioMedicine, Vol. 36, pp. 29-38, (2019) (PubMed).

Détails sur APOE

Antigène: APOE (Apolipoprotein E (APOE))

Autre désignation: APOE

Sujet: Background: Anti Apolipoprotein E Antibody recognizes the gene product of APOE. Apolipoprotein E is found in the chylomicron and IDLs that binds to a specific receptor on liver cells and peripheral cells. Apolipoprotein E is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. This antibody is suitable for cardiovascular research.

ID gène: 348

NCBI Accession: NP_000032

UniProt: P02649

Pathways: Regulation of Cell Size, Lipid Metabolism