Stim2 anticorps (C-Term)

N° du produit ABIN5596756

Détail du produit anti-Stim2 anticorps

Antigène: Stim2 (Stromal Interaction Molecule 2 (Stim2))

Épitope: C-Term

Reactivité: Humain

Hôte: Mouton

Clonalité: Polyclonal

Conjugué: Cet anticorp Stim2 est non-conjugé

Application: Western Blotting (WB), ELISA

Réactivité croisée (Details): A BLAST analysis was used to suggest cross-reactivity with mouse and human based on 100% sequence homology. Cross-reactivity with Stim II from other sources has not been determined.

Purification: Anti-Stim II was affinity purified from monospecific antiserum by immunoaffinity chromatography.

Immunogène:

Immunogen: Stim II affinity purified antibody was prepared from whole sheep serum produced by repeated immunizations with a synthetic peptide near the C-terminus of human Stim II.

Immunogen Type: Peptide

Isotype: IgG

Information d'application

Indications d'application:

Application Note: Anti-Stim II antibody is useful for ELISA, immunohistochemistry, and Western Blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~84 kDa corresponding to the appropriate cell lysate or extract.

Western Blot Dilution: 1 μg/mL

ELISA Dilution: 1: 10,000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.1 mg/mL

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: 30 % Glycerol

Stock: 4 °C,-20 °C

Stockage commentaire: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Date de péremption: 12 months

Détails sur Stim2

Antigène: Stim2 (Stromal Interaction Molecule 2 (Stim2))

Autre désignation: Stim2 (Stim2 Produits)

Synonymes: anticorps STIM2, anticorps stromal interaction molecule 2, anticorps STIM2, anticorps stim2, anticorps Stim2

Sujet:

Synonyms: Stromal interaction molecule 2, STIM2

Background: Stim II antibody functions as a calcium sensor in the endoplasmic reticulum via its EF-hand domain. After depletion of Ca+2, it is thought to translocate from the endoplasmic reticulum to the plasma membrane to activate the calicum release-activated channel subunit. It may inhibit STIM1-mediated calcium influx. Anti-Stim II antibody is ideal for investigators interested in Signal Transduction research.

Gene Name: STIM2

Pathways: TCR Signaling, BCR Signaling