PPARG anticorps (pSer273)

N° du produit ABIN5596784

N° du produit (Fournisseur): 600-401-j94

Cet anticorps Lapin Polyclonal détecte spécifiquement PPARG dans WB, IHC, ELISA et DB. Il présente une réactivité envers Humain.

Aperçu rapide pour PPARG anticorps (pSer273) (ABIN5596784)

Antigène: PPARG (Peroxisome Proliferator-Activated Receptor gamma (PPARG))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PPARG est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Dot Blot (DB)

Détail du produit anti-PPARG anticorps

Épitope: pSer273

N° du produit (Fournisseur): 600-401-j94

Fournisseur: Rockland

Fonction: PPAR gamma phospho S273 Antibody

Réactivité croisée (Details): A BLAST analysis was used to suggest cross-reactivity with rat, mouse, primate, human, dog, bovine, and pig based on 100 % sequence homology.

Attributs du produit: Synonyms: rabbit anti-PPAR gamma pS273 antibody, Peroxisome proliferator-activated receptor gamma, Nuclear receptor subfamily 1 group C member 3, NR1C3, PPARG, PPAR gamma

Purification: Anti-PPAR gamma pS273 was affinity purified from monospecific antiserum by immunoaffinity chromatography and is directed against the phosphorylated form of human PPAR gamma at the S273 residue.

Stérilité: Sterile filtered

Immunogène:

Immunogen: Anti-PPAR gamma pS273 affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to the internal region of human PPARG protein.

Immunogen Type: Conjugated Peptide

Isotype: IgG

Information d'application

Indications d'application:

Immunohistochemistry Dilution: User Optimized

Application Note: Anti-PPAR antibody has been tested by ELISA and dot blot and is useful for Immunohistochemistry and Western Blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~57 kDa corresponding to the appropriate cell lysate or extract.

Western Blot Dilution: 1 μg/mL

ELISA Dilution: 1: 10,000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.85 mg/mL

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: None

Preservative: 0.05 % (w/v) Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Date de péremption: 12 months

Détails sur PPARG

Antigène: PPARG (Peroxisome Proliferator-Activated Receptor gamma (PPARG))

Autre désignation: PPARG

Sujet: Background: PPAR has a receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. The receptor, when activated by ligand, binds to a promotor element in the gene for acyl-CoA oxidase and activates its transcription. In this way it controls the peroxisomal beta-oxidation pathway of fatty acids. It plays a key role in regulating adipocyte differentiation, gut homeostasis, and glucose homeostasis. Anti-PPAR gamma pS273 Antibody is ideal for researchers interested in Metabolism, Cardiovascular or Neuroscience research.

ID gène: 5468, 20336229

UniProt: P37231

Pathways: Signalisation MAPK, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Regulation of Lipid Metabolism by PPARalpha, Positive Regulation of Endopeptidase Activity, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation