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Adenosine A2a Receptor anticorps (AA 274-412)

ADORA2A Reactivité: Humain WB, ELISA, IHC, FACS, ICC, Neut Hôte: Souris Monoclonal 6A6G11 unconjugated
N° du produit ABIN5611128
  • Antigène Voir toutes Adenosine A2a Receptor (ADORA2A) Anticorps
    Adenosine A2a Receptor (ADORA2A)
    Épitope
    • 12
    • 9
    • 7
    • 7
    • 7
    • 7
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 274-412
    Reactivité
    • 79
    • 30
    • 29
    • 9
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 70
    • 10
    • 2
    Souris
    Clonalité
    • 74
    • 7
    • 1
    Monoclonal
    Conjugué
    • 51
    • 7
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Adenosine A2a Receptor est non-conjugé
    Application
    • 69
    • 34
    • 29
    • 17
    • 13
    • 12
    • 7
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC), Neutralization (Neut)
    Purification
    purified
    Immunogène
    Purified recombinant fragment of human ADORA2A (AA: 274-412) expressed in E. coli.
    Clone
    6A6G11
    Isotype
    IgG2a
    Top Product
    Discover our top product ADORA2A Anticorps primaire
  • Indications d'application
    ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: 1:100 - 1:500, FCM: 1:200 - 1:400, IHC: N/A
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    4°C, -20°C for long term storage
  • Antigène
    Adenosine A2a Receptor (ADORA2A)
    Autre désignation
    ADORA2A (ADORA2A Produits)
    Synonymes
    anticorps ADORA2A, anticorps adora2a.1, anticorps zgc:194773, anticorps A2aR, anticorps ADORA2, anticorps RDC8, anticorps A2AAR, anticorps AA2AR, anticorps A2ar, anticorps ADENO, anticorps Adora2l1, anticorps adora2a.2, anticorps zgc:193802, anticorps zgc:193822, anticorps adenosine A2a receptor, anticorps adenosine A2a receptor a, anticorps adenosine A2a receptor L homeolog, anticorps adenosine A2a receptor b, anticorps ADORA2A, anticorps Adora2a, anticorps adora2aa, anticorps adora2a.L, anticorps adora2a, anticorps adora2ab
    Sujet

    Description: This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor (GPCR) superfamily, which is subdivided into classes and subtypes. The receptors are seven-pass transmembrane proteins that respond to extracellular cues and activate intracellular signal transduction pathways. This protein, an adenosine receptor of A2A subtype, uses adenosine as the preferred endogenous agonist and preferentially interacts with the G(s) and G(olf) family of G proteins to increase intracellular cAMP levels. It plays an important role in many biological functions, such as cardiac rhythm and circulation, cerebral and renal blood flow, immune function, pain regulation, and sleep. It has been implicated in pathophysiological conditions such as inflammatory diseases and neurodegenerative disorders. Alternative splicing results in multiple transcript variants. A read-through transcript composed of the upstream SPECC1L (sperm antigen with calponin homology and coiled-coil domains 1-like) and ADORA2A (adenosine A2a receptor) gene sequence has been identified, but it is thought to be non-coding.

    Aliases: A2aR, RDC8, ADORA2

    Poids moléculaire
    44.7 kDa
    ID gène
    135
    HGNC
    135
    Pathways
    Neurotrophin Signaling Pathway, cAMP Metabolic Process, Synaptic Membrane, Feeding Behaviour, Cancer Immune Checkpoints
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