Integrin beta 4 anticorps (AA 29-206)
Aperçu rapide pour Integrin beta 4 anticorps (AA 29-206) (ABIN5611134)
Antigène
Voir toutes Integrin beta 4 (ITGB4) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 29-206
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Fonction
- CD104 Antibody
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Purification
- Purified antibody
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Immunogène
- Purified recombinant fragment of human CD104 (AA: 29-206) expressed in E. Coli.
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Isotype
- IgG2a
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Indications d'application
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Integrin beta 4 (ITGB4)
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Autre désignation
- CD104
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Sujet
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Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
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Poids moléculaire
- 202.2 kDa
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ID gène
- 3691
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UniProt
- P16144
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Pathways
- Integrin Complex
Antigène
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