Metabotropic Glutamate Receptor 3 anticorps (AA 433-576)

N° du produit ABIN5611176

L’anticorps Souris Monoclonal anti-Metabotropic Glutamate Receptor 3 a été validé pour ELISA, IHC et FACS. Il convient pour détecter Metabotropic Glutamate Receptor 3 dans des échantillons de Humain.

Aperçu rapide pour Metabotropic Glutamate Receptor 3 anticorps (AA 433-576) (ABIN5611176)

Antigène: Metabotropic Glutamate Receptor 3 (GRM3) (Glutamate Receptor, Metabotropic 3 (GRM3))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Metabotropic Glutamate Receptor 3 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Clone: 6H10C3

Détail du produit anti-Metabotropic Glutamate Receptor 3 anticorps

Épitope: AA 433-576

Fonction: GRM3 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human GRM3 (AA: 433-576) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur Metabotropic Glutamate Receptor 3

Antigène: Metabotropic Glutamate Receptor 3 (GRM3) (Glutamate Receptor, Metabotropic 3 (GRM3))

Autre désignation: GRM3

Sujet: L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.

Poids moléculaire: 99 kDa

ID gène: 2913

UniProt: Q14832

Pathways: cAMP Metabolic Process, Synaptic Membrane