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Metabotropic Glutamate Receptor 3 anticorps (AA 433-576)

GRM3 Reactivité: Humain WB, ELISA, IHC, FACS, ICC, Neut Hôte: Souris Monoclonal 6H10C3 unconjugated
N° du produit ABIN5611176
  • Antigène Voir toutes Metabotropic Glutamate Receptor 3 (GRM3) Anticorps
    Metabotropic Glutamate Receptor 3 (GRM3) (Glutamate Receptor, Metabotropic 3 (GRM3))
    Épitope
    • 16
    • 10
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 433-576
    Reactivité
    • 40
    • 31
    • 14
    • 11
    • 7
    • 6
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    Humain
    Hôte
    • 55
    • 1
    • 1
    Souris
    Clonalité
    • 55
    • 2
    Monoclonal
    Conjugué
    • 24
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Metabotropic Glutamate Receptor 3 est non-conjugé
    Application
    • 44
    • 19
    • 16
    • 9
    • 9
    • 5
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC), Neutralization (Neut)
    Purification
    purified
    Immunogène
    Purified recombinant fragment of human GRM3 (AA: extra 433-576) expressed in E. coli.
    Clone
    6H10C3
    Isotype
    IgG1
  • Indications d'application
    ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: N/A, FCM: 1:200 - 1:400, IHC: 1:200 - 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    4°C, -20°C for long term storage
  • Antigène
    Metabotropic Glutamate Receptor 3 (GRM3) (Glutamate Receptor, Metabotropic 3 (GRM3))
    Autre désignation
    GRM3 (GRM3 Produits)
    Sujet

    Description: L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.

    Aliases: GLUR3, mGlu3, GPRC1C, MGLUR3

    Poids moléculaire
    99 kDa
    ID gène
    2913
    HGNC
    2913
    Pathways
    cAMP Metabolic Process, Synaptic Membrane
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