Neuropilin 1 anticorps (AA 22-644)

N° du produit ABIN5611190

Cet anticorps Souris Monoclonal détecte spécifiquement Neuropilin 1 dans ELISA. Il présente une réactivité envers Humain.

Aperçu rapide pour Neuropilin 1 anticorps (AA 22-644) (ABIN5611190)

Antigène: Neuropilin 1 (NRP1)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Neuropilin 1 est non-conjugé

Application: ELISA

Clone: 5H11G6

Détail du produit anti-Neuropilin 1 anticorps

Épitope: AA 22-644

Fonction: NRP1 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human NRP1 (AA: 22-644) expressed in HEK293 cells.

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur Neuropilin 1

Antigène: Neuropilin 1 (NRP1)

Autre désignation: NRP1

Sujet: This gene encodes one of two neuropilins, which contain specific protein domains which allow them to participate in several different types of signaling pathways that control cell migration. Neuropilins contain a large N-terminal extracellular domain, made up of complement-binding, coagulation factor V/VIII, and meprin domains. These proteins also contains a short membrane-spanning domain and a small cytoplasmic domain. Neuropilins bind many ligands and various types of co-receptors, they affect cell survival, migration, and attraction. Some of the ligands and co-receptors bound by neuropilins are vascular endothelial growth factor (VEGF) and semaphorin family members. Several alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.

Poids moléculaire: 103.1 kDa

ID gène: 8829

UniProt: O14786

Pathways: Regulation of Cell Size, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, VEGFR1 Specific Signals