CCR1 anticorps

N° du produit ABIN5611256

Cet anticorps Souris Monoclonal détecte spécifiquement CCR1 dans ELISA, WB et FACS. Il présente une réactivité envers Humain.

Aperçu rapide pour CCR1 anticorps (ABIN5611256)

Antigène: CCR1 (Chemokine (C-C Motif) Receptor 1 (CCR1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CCR1 est non-conjugé

Application: ELISA, Western Blotting (WB), Flow Cytometry (FACS)

Clone: 8E10F9

Détail du produit anti-CCR1 anticorps

Fonction: CD191 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human CD191 (AA: mix) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur CCR1

Antigène: CCR1 (Chemokine (C-C Motif) Receptor 1 (CCR1))

Autre désignation: CD191

Sujet: This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The ligands of this receptor include macrophage inflammatory protein 1 alpha (MIP-1 alpha), regulated on activation normal T expressed and secreted protein (RANTES), monocyte chemoattractant protein 3 (MCP-3), and myeloid progenitor inhibitory factor-1 (MPIF-1). Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. Knockout studies of the mouse homolog suggested the roles of this gene in host protection from inflammatory response, and susceptibility to virus and parasite. This gene and other chemokine receptor genes, including CCR2, CCRL2, CCR3, CCR5 and CCXCR1, are found to form a gene cluster on chromosome 3p.

Poids moléculaire: 41.2 kDa

UniProt: P32246