DDR1 anticorps (AA 21-176)

N° du produit ABIN5611283

Cet anticorps Souris Monoclonal détecte spécifiquement DDR1 dans ELISA et FACS. Il présente une réactivité envers Humain.

Aperçu rapide pour DDR1 anticorps (AA 21-176) (ABIN5611283)

Antigène: DDR1 (Discoidin Domain Receptor tyrosine Kinase 1 (DDR1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp DDR1 est non-conjugé

Application: ELISA, Flow Cytometry (FACS)

Clone: 4F2C12

Détail du produit anti-DDR1 anticorps

Épitope: AA 21-176

Fonction: CD167 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human CD167 (AA: 21-176) expressed in E. Coli.

Isotype: IgG2b

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur DDR1

Antigène: DDR1 (Discoidin Domain Receptor tyrosine Kinase 1 (DDR1))

Autre désignation: CD167

Sujet: Receptor tyrosine kinases play a key role in the communication of cells with their microenvironment. These kinases are involved in the regulation of cell growth, differentiation and metabolism. The protein encoded by this gene belongs to a subfamily of tyrosine kinase receptors with homology to Dictyostelium discoideum protein discoidin I in their extracellular domain, and that are activated by various types of collagen. Expression of this protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, it has been shown to be significantly overexpressed in several human tumors. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Poids moléculaire: 101 kDa

UniProt: Q08345

Pathways: Signalisation RTK, Smooth Muscle Cell Migration