HSD17B3 anticorps (AA 29-119)

N° du produit ABIN561372

Cité dans 3 publications. Cet anticorps anti-HSD17B3 Polyclonal Souris (ABIN561372) détecte spécifiquement HSD17B3 dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour HSD17B3 anticorps (AA 29-119) (ABIN561372)

Antigène: HSD17B3 (Hydroxysteroid (17-Beta) Dehydrogenase 3 (HSD17B3))

Reactivité: Humain

Hôte: Souris

Clonalité: Polyclonal

Conjugué: Cet anticorp HSD17B3 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-HSD17B3 anticorps

Épitope: AA 29-119

Fonction: Mouse polyclonal antibody raised against a partial recombinant HSD17B3.

Séquence: RCVLLNYWKV LPKSFLRSMG QWAVITGAGD GIGKAYSFEL AKRGLNVVLI SRTLEKLEAI ATEIERTTGR SVKIIQADFT KDDIYEHIKE K

Réactivité croisée: Humain, Souris

Attributs du produit: Antibody Reactive Against Recombinant Protein.

Immunogène: HSD17B3 (NP_000188, 29 a.a. ~ 119 a.a) partial recombinant protein with GST tag.

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 50 % glycerol

Conseil sur la manipulation: Aliquot to avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-HSD17B3 (ABIN561372)

Fokidis, Yieng Chin, Ho, Adomat, Soma, Fazli, Nip, Cox, Krystal, Zoubeidi, Tomlinson Guns: "A low carbohydrate, high protein diet suppresses intratumoral androgen synthesis and slows castration-resistant prostate tumor growth in mice." dans: The Journal of steroid biochemistry and molecular biology, Vol. 150, pp. 35-45, (2015) (PubMed).

Ming, Pham, Deb, Chin, Kharmate, Adomat, Beheshti, Locke, Guns: "Pomegranate extracts impact the androgen biosynthesis pathways in prostate cancer models in vitro and in vivo." dans: The Journal of steroid biochemistry and molecular biology, Vol. 143, pp. 19-28, (2014) (PubMed).

Locke, Guns, Lubik, Adomat, Hendy, Wood, Ettinger, Gleave, Nelson: "Androgen levels increase by intratumoral de novo steroidogenesis during progression of castration-resistant prostate cancer." dans: Cancer research, Vol. 68, Issue 15, pp. 6407-15, (2008) (PubMed).

Détails sur HSD17B3

Antigène: HSD17B3 (Hydroxysteroid (17-Beta) Dehydrogenase 3 (HSD17B3))

Autre désignation: HSD17B3

Sujet: Full Gene Name: hydroxysteroid (17-beta) dehydrogenase 3
Synonyms: EDH17B3,SDR12C2

ID gène: 3293

NCBI Accession: NM_000197

Pathways: Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis