ISL1 anticorps (AA 63-159)

N° du produit ABIN561536

Il existe 5+ publications pour ce produit. L’anticorps anti-ISL1 Monoclonal Souris est utilisé pour la détection de ISL1 dans des échantillons de Humain. Il a été validé pour WB, ELISA et IF.

Aperçu rapide pour ISL1 anticorps (AA 63-159) (ABIN561536)

Antigène: ISL1 (ISL LIM Homeobox 1 (ISL1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ISL1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Clone: 2E7

Détail du produit anti-ISL1 anticorps

Épitope: AA 63-159

Fonction: Mouse monoclonal antibody raised against a partial recombinant ISL1.

Séquence: YCKRDYIRLY GIKCAKCSIG FSKNDFVMRA RSKVYHIECF RCVACSRQLI PGDEFALRED GLFCRADHDV VERASLGAGD PLSPLHPARP LQMAAEP

Réactivité croisée: Humain, Rat

Attributs du produit: Antibody Reactive Against Recombinant Protein.

Immunogène: ISL1 (NP_002193, 63 a.a. ~ 159 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2a

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: In 1x PBS, pH 7.4

Conseil sur la manipulation: Aliquot to avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-ISL1 (ABIN561536)

Tian, Wang, Lu, Chen, Ma, Jia, Zhou: "Cross-talk of SFRP4, integrin α1β1, and Notch1 inhibits cardiac differentiation of P19CL6 cells." dans: Cellular signalling, Vol. 28, Issue 11, pp. 1806-15, (2016) (PubMed).

Zhang, Yang, Wang, Guo, Jia, Ma, Zhou: "A positive feedback regulation of ISL-1 in DLBCL but not in pancreatic ?-cells." dans: Biochemical and biophysical research communications, Vol. 449, Issue 3, pp. 295-300, (2014) (PubMed).

Zhang, Yang, Jia, Liu, Guo, Lu, Chen, Ma, Wang, Zhou: "ISL-1 is overexpressed in non-Hodgkin lymphoma and promotes lymphoma cell proliferation by forming a p-STAT3/p-c-Jun/ISL-1 complex." dans: Molecular cancer, Vol. 13, pp. 181, (2014) (PubMed).

Li, Jia, Wang, Wang, Zhang, Chen, Ma, Zhou: "Interaction of Wnt/?-catenin and notch signaling in the early stage of cardiac differentiation of P19CL6 cells." dans: Journal of cellular biochemistry, Vol. 113, Issue 2, pp. 629-39, (2012) (PubMed).

Guo, Wang, Zhang, Liu, Chen, Ma, Zhou: "ISL1 promotes pancreatic islet cell proliferation." dans: PLoS ONE, Vol. 6, Issue 8, pp. e22387, (2011) (PubMed).

Détails sur ISL1

Antigène: ISL1 (ISL LIM Homeobox 1 (ISL1))

Autre désignation: ISL1

Sujet: Full Gene Name: ISL LIM homeobox 1
Synonyms: Isl-1

ID gène: 3670

NCBI Accession: NM_002202

Pathways: Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Chromatin Binding