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Recombinant ISL1 anticorps

ISL1 Reactivité: Humain WB, ELISA, IHC Hôte: Lapin Monoclonal 1A1 unconjugated Recombinant Antibody
N° du produit ABIN7127582
  • Antigène Voir toutes ISL1 Anticorps
    ISL1 (ISL LIM Homeobox 1 (ISL1))
    Type d'anticorp
    Recombinant Antibody
    Reactivité
    • 70
    • 44
    • 27
    • 8
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 67
    • 11
    Lapin
    Clonalité
    • 56
    • 22
    Monoclonal
    Conjugué
    • 41
    • 6
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ISL1 est non-conjugé
    Application
    • 59
    • 30
    • 14
    • 13
    • 7
    • 7
    • 6
    • 5
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
     Réactivité croisée
    Humain
    Purification
    Affinity-chromatography
    Immunogène
    A synthesized peptide derived from human Islet1
    Clone
    1A1
    Isotype
    IgG
    Top Product
    Discover our top product ISL1 Anticorps primaire
  • Indications d'application
    Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    ISL1 (ISL LIM Homeobox 1 (ISL1))
    Autre désignation
    ISL1 (ISL1 Produits)
    Synonymes
    anticorps Xisl-1, anticorps Xislet-1, anticorps islet1, anticorps ISLET-1, anticorps ISLET1, anticorps Isl-1, anticorps islet-1, anticorps isl-1=homeobox, anticorps Islet-1, anticorps ISL LIM homeobox 1 S homeolog, anticorps ISL LIM homeobox 1, anticorps ISL1 transcription factor, LIM/homeodomain, anticorps isl1.S, anticorps ISL1, anticorps Isl1, anticorps isl1
    Sujet

    Background: DNA-binding transcriptional activator. Recognizes and binds to the consensus octamer binding site 5'-ATAATTAA-3' in promoter of target genes. Plays a fundamental role in the gene regulatory network essential for retinal ganglion cell (RGC) differentiation. Cooperates with the transcription factor POU4F2 to achieve maximal levels of expression of RGC target genes and RGC fate specification in the developing retina. Involved in the specification of motor neurons in cooperation with LHX3 and LDB1. Binds to insulin gene enhancer sequences.

    Aliases: Insulin gene enhancer protein ISL-1 (Islet-1), ISL1

    UniProt
    P61371
    Pathways
    Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Chromatin Binding
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